Scientists have known that a restricted diet can extend lifespans. According to the American Association for Long-Term Care Insurance. the new research shows that effects occur even if the restricted diet is adopted later in life.
“These findings could help scientists to better understand and ultimately prevent a range of age-related diseases in humans.” according to Jesse Slome, executive diirector of the organization. “When you live a long life however you are far more likely to need long term care.”
The research was conducted by scientists at the British Society for Research on Ageing at Newcastle University.
Working with the theory that cell senescence – the point at which a cell can no longer replicate – is a major cause of ageing the researchers set out to investigate what effect a restricted diet had on this process. By looking at mice fed a restricted diet the team found that they had a reduced accumulation of senescent cells in their livers and intestines. Both organs are known to accumulate large numbers of these cells as animals age.
Alongside this the CISBAN scientists also found that the telomeres of the chromosomes of the mice on restricted diets were better maintained despite their ageing. Telomeres are the protective ‘ends’ of chromosomes that prevent errors, and therefore diseases, occurring as DNA replicates throughout an organisms lifetime but they are known to become ‘eroded’ over time.
The adult mice were fed a restricted diet for a short period of time demonstrating that it may not be necessary to follow a very low calorie diet for a lifetime to gain the benefits the scientists found.
Researchers looked at parts of the body that easily show biological signs of ageing, suggests that a restricted diet can help to reduce the amount of cell senescence occurring and can reduce damage to protective telomeres. In turn this prevents the accumulation of damaging tissue oxidation which would normally lead to age-related disease.
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